M. Pharm Il Semester Supplementary Examinations, February 2016
NOVEL DRUG DELIVERY SYSTEMS II
(Pharmaceutics)
Time: 3 hours Max. Marks: 60
Answer any FIVE questions
All questions carry equal marks
1 Explain physiological factors affecting bioavailability
2 (a) Explain Lymphatic transport of drugs.
(b) Write short notes on inter cellular route of absorption.
3 (a) Give clinical applications of gene therapy.
(b) Explain liposomal gene delivery.
4 (a) Explain current gene therapy of Hepatitis
(b) Explain current gene therapy of AIDs.
5 (a) Discuss formulation aspects of delivery of peptides and protein.
(b) Discuss briefly derivatives of antibodies.
6 (a) Explain controlled release micro-particles for vaccine development.
(b) Explain various evaluation methods of colon specific systems
7 (a) Define active and passive targeting. Explain molecular basis of drug targeting.
(b) Explain limitations of antibody targeting.
8 (a) Explain principle involved and formulation of nano particles.
(b) Write short notes on Resealed erythrocytes.
